Comparison of Applied Behavioral Analysis (ABA) Versus ABA and Risperidone

Completed · Not applicable

Conditions studied: Autistic Disorder

In brief

Hypotheses: 1. Preschool children with autism spectrum disorders (ASDs) who undergo ABA treatment only will demonstrate significantly better outcomes compared to an age and severity matched control group without ABA treatment. 2. Preschool children with ASDs who undergo ABA in combination with risperidone will demonstrate significantly better outcomes compared to age and severity matched children who are receiving ABA alone. 3. Young age, cognitive development and attentional abilities at baseline will be predictive of good socio-emotional and neuropsychological outcomes after ABA treatment. 4. At baseline, children with ASDs will show significantly lower performances on measures of cognitive, neuropsychological, and socio-emotional functioning than age-matched typically developing controls.

Key facts

Study ID

NCT00374764

Run by

Washington University School of Medicine

People needed

60

Starts

2000-07-01

Expected to finish

2002-06-01

Last updated by the study team

2007-02-16

Who can join

Age: 3 and older, up to 5. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Diagnosis of autism or severe pervasive developmental disorder (PDD) not otherwise specified (NOS) according to the Autism Diagnosis Interview-Revised (ADI-R)
• Aged 2.6 to 5.0.

You may not qualify if…

• Fragile X or metabolic etiology of PDD symptoms
• Diagnosis of other central nervous system (CNS) disorders
• Chronic serious medical problems

Where it is running

• Early Emotional Development Program — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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