Aripiprazole in the Treatment of Patients With Schizophrenia and Symptoms of Obsessive Compulsive Disorder (OCD)

Completed · Not applicable

Conditions studied: Schizophrenia OCD, Obsessive Compulsive Disorder

In brief

To evaluate the effectiveness of flexible doses (15-30mg) of Aripiprazole in the treatment of patients with schizophrenia and co-morbid symptoms of OCD in the outpatient setting. The overall effectiveness of Aripiprazole will be evaluated by use of the Brief Psychiatric Rating Scale(BPRS), Yale-Brown OCD scale and Clinical Global Impression-Improvement(CGI-I) scale.

Key facts

Study ID

NCT00374348

Run by

Jamaica Hospital Medical Center

People needed

10

Starts

2005-03-01

Expected to finish

2008-05-01

Last updated by the study team

2011-09-16

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Man and Women 18-65 years of age.
• Patients who are capable of giving Informed Consent and fluent in English.
• Patients who have DSM IV -Diagnosis of schizophrenia with co-morbid OCD symptoms and BPRS score averaging from mild to moderate (3-4).
• Patients whose obsessive symptoms are not optimally controlled and require a change of treatment.YBOCS score of more than 16.

You may not qualify if…

• Outside the age range of 18-65 years.
• Patients with current evidence(past three months) of substance abuse.
• Women of child bearing age who are unwilling to use acceptable methods of contraception.
• Patients who have had recent treatment with long-acting antipsychotic.
• Patients who are suicidal or who have history of recent suicidal attempt.
• History of significant medical condition e.g. seizures, cardiovascular, endocrine,gastrointestinal,renal or respiratory diseases.

Where it is running

• Jamaica Hospital Medical Center Department of Psychiatry — Jamaica, New York, United States

Full record on ClinicalTrials.gov

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