Study of Apixaban for the Prevention of Thrombosis-related Events Following Knee Replacement Surgery
Completed · Phase 3 · Has a placebo group
Conditions studied: Deep Vein Thrombosis, Pulmonary Embolism
In brief
The purpose of this study is to learn if apixaban can prevent blood clots in the leg (deep vein Thrombosis \[DVT\]) and lung (pulmonary embolism \[PE\]) that sometimes occur after knee replacement surgery and to learn how apixaban compares to enoxaparin (Lovenox®) for preventing these clots. The safety of apixaban will also be studied.
Key facts
- Study ID
- NCT00371683
- Run by
- Bristol-Myers Squibb
- People needed
- 3608
- Starts
- 2006-11-01
- Expected to finish
- 2008-05-01
- Last updated by the study team
- 2015-12-30
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Capstone Clinical Trials, Inc — Birmingham, Alabama, United States
- West Alabama Research, Inc. — Tuscaloosa, Alabama, United States
- Martin Bowen Hefley Orthopedics — Little Rock, Arkansas, United States
- Colorado Orthopedic Consultants, Pc — Aurora, Colorado, United States
- Colorado Joint Replacement — Denver, Colorado, United States
- Jdpmedical Research — Denver, Colorado, United States
- Orhtopaedic Physicians Of Colorado, P.C. — Englewood, Colorado, United States
- Orthopedics Assocs Of Hartford — Hartford, Connecticut, United States
- Anthony S. Unger, Md — Washington D.C., District of Columbia, United States
- Bay Pines Va Medical Center — Bay Pines, Florida, United States
- Pab Clinical Research — Brandon, Florida, United States
- Jacksonville Center For Clinical Research — Jacksonville, Florida, United States
- Mark W. Hollmann, Md — Orange City, Florida, United States
- Jewett Orthopaedic Clinic — Winter Park, Florida, United States
- Atlanta Knee And Sports Medicine — Decatur, Georgia, United States
- Americana Orthopedics — Boise, Idaho, United States
- Intermountain Orthopaedics — Boise, Idaho, United States
- Bluegrass Orthopaedics/Bmr — Lexington, Kentucky, United States
- Charleston Orthopaedic Assocs. — Charleston, South Carolina, United States
- Kelsey Seybold Clinic — Houston, Texas, United States
- Bone & Joint Clinic Of Houston — Houston, Texas, United States
- Gill Orthopedic Center — Lubbock, Texas, United States
- Robert R. King, Md — Lubbock, Texas, United States
- Unlimited Research — San Antonio, Texas, United States
- Capstone Clinical Trials, Inc — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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