Timing of Cord Clamping and Neonatal Hemoglobin
Withdrawn before enrolling · Not applicable
Conditions studied: Anemia
In brief
The purpose of this study is to determine whether the timing of the clamping of the umbilical cord after delivery has an impact on neonatal hemoglobin and hematocrit, tests that determine the number of red cells in the blood and their ability to carry oxygen. The study hypothesis is that delaying cord clamping until cord pulsation has ceased will increase the neonatal blood volume and thereby increase the hemoglobin and hematocrit. We propose to recruit 150 women who present for vaginal delivery at Tulsa Regional Medical Center. Half of the women will be randomly assigned to the immediate clamping group, which will entail clamping of the umbilical cord within six seconds of delivery of the fetal shoulders. The other half of the volunteers will be assigned to the delayed clamping group, which will entail clamping the cord after a palpable pulse has ceased, or after 10 minutes. The infants of mothers in both groups will have blood drawn for a hemoglobin and hematocrit at the time of the routine PKU heel stick, usually is performed within 18-24 hours of delivery. Statistical differences between the blood counts of infants in the control and study groups will be compared using independent samples t tests.
Key facts
- Study ID
- NCT00371228
- Run by
- Oklahoma State University Center for Health Sciences
- People needed
- 0
- Starts
- 2006-09-01
- Expected to finish
- 2009-06-01
- Last updated by the study team
- 2020-10-05
Who can join
Age: 18 and older, up to 34. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Healthy women and their newborn infants delivered at Tulsa Regional Medical Center,
- between the ages of 18 and 34,
- full term (37 to 41 weeks),
- singleton pregnancy at the time of delivery
You may not qualify if…
- Delivery complicated by non-reassuring fetal heart tones,
- preeclampsia,
- eclampsia,
- chronic hypertension,
- meconium-stained amniotic fluid,
- fetal anomalies or
- any other condition which could require immediate newborn evaluation by nursery personnel at the time of delivery. Infants requiring operative delivery by forceps or vacuum also will be excluded.
Where it is running
- OSU Houston Center — Tulsa, Oklahoma, United States
Full record on ClinicalTrials.gov
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