A Study of Nimotuzumab in Combination With External Radiotherapy in Non-Small Cell Lung Cancer
Stopped early · Phase 1/Phase 2
Conditions studied: Non-small-cell Lung Cancer
In brief
This is a Phase I-II study designed to investigate nimotuzumab (TheraCIM h-R3) in combination with external radiation in patients with non-small cell lung cancer. The purpose of the Phase I portion of the study is to evaluate the safety and feasibility of the administration of nimotuzumab with palliative radiation in patients who are unsuitable for radical therapy and to select the optimal dose for the Phase II component of the study. The primary objective for the Phase II portion of the study is to examine the efficacy of this combination treatment. The Phase I component of this study has been completed. The Phase II is now closed to recruitment.
Key facts
- Study ID
- NCT00369447
- Run by
- YM BioSciences
- People needed
- 52
- Starts
- 2009-03-01
- Expected to finish
- 2011-07-01
- Last updated by the study team
- 2011-07-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Florida Cancer Institute - New Hope — New Port Richey, Florida, United States
- Tom Baker Cancer Center — Calgary, Alberta, Canada
- Cancer Centre for the Southern Interior — Kelowna, British Columbia, Canada
- Dr. H. Bliss Murphy Cancer Centre — St. John's, Newfoundland and Labrador, Canada
- London Regional Cancer Center — London, Ontario, Canada
- The Ottawa Hospital Cancer Centre — Ottawa, Ontario, Canada
- Thunderbay Regional hospital Center — Thunderbay, Ontario, Canada
- Princess Margaret Hospital — Toronto, Ontario, Canada
- Hopital Maisonneuve-Rosemont — Montreal, Quebec, Canada
- Centre Hospitalier de L'Universite de Montreal - Hôpital Notre Dame — Montreal, Quebec, Canada
- Segal Cancer Center - Jewish General Hospital — Montreal, Quebec, Canada
- Hotel Dieu Hospital — Québec, Quebec, Canada
- National Cancer Center Singapore — Singapore, Singapore
Full record on ClinicalTrials.gov
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