Energy Homeostasis in Anorexia Nervosa

Completed

Conditions studied: Anorexia Nervosa

In brief

The purpose of this study is to investigate the potential biological predispositions that contribute to the difficulty patients with anorexia nervosa have in maintaining normal weight.

Key facts

Study ID

NCT00368667

Run by

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

People needed

120

Starts

2000-04-01

Expected to finish

2004-12-01

Last updated by the study team

2010-01-13

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• DSM-IV diagnosis of Anorexia Nervosa
• BMI ≤ 17.5kg/m2 (equivalent to 80% of ideal body weight)
• Medically stable
• Participation in in-patient treatment sufficient to restore patient to a BMI of at least 19kg/m2

You may not qualify if…

• On medication*
• Current substance abuse or dependence
• History of suicide attempt or other self-injurious behavior within the previous 6 months
• Non-removable metal on/in their body (e.g. metal pacemaker, surgical clips, metallic-ink tattoos)
• Controls:
• Inclusion criteria:
• No current psychiatric disorder (including eating disorder, depression, bipolar disorder, schizophrenia, substance abuse/dependence)
• No history of an eating disorder
• BMI greater than 19kg/m2 and less than 21kg/m2
• Weight stable (+/- 2kg) for the previous 6 months
• No history of excessive or repeated dieting
• No history of excessive exercise (defined as greater than 6 hours/week)
• Regular menstrual cycles
• Exclusion criteria:
• On medication*
• Pregnant or lactating
• Significant medical problem
• Non-removable metal on/in their body (e.g. metal pacemaker, surgical clips, metallic-ink tattoos)
• At the time of testing, subjects will be free of fluoxetine for 6 weeks, and free of all other medications for a minimum of 2 weeks

Where it is running

• New York State Psychiatric Institute, Unit 98 — New York, New York, United States

Full record on ClinicalTrials.gov

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