Parkinson's Genes and Environment Study
Completed
Conditions studied: Parkinson's Disease
In brief
This study will examine the roles of diet, lifestyle, genes, and their possible interactions in the cause of Parkinson's disease, using information from the NIH-AARP Diet and Health Study. The NIH-AARP study was established in 1995 to examine the roles of diet and lifestyle in cancer. It included 567,169 AARP members 50 or older from California, Florida, North Carolina, Pennsylvania, New Jersey, Louisiana, and the Atlanta and Detroit metropolitan areas. In 1995, participants completed a comprehensive questionnaire on diet and a survey on demographics, medications, as well as a follow-up survey in 1996 with more detailed questions on lifestyle and medications, as well as cooking methods and early life dietary habits. A third followup survey is currently underway. The current NIH-AARP substudy on Parkinson's disease will include approximately 9,000 participants from the NIH-AARP study - 3,000 of whom reported being diagnosed with Parkinson's disease on the most recent survey, and 6,000 control subjects. These study participants provide two saliva samples for genetic analysis and may be asked to complete a telephone interview. In addition, those with Parkinson's disease are asked permission to review medical information regarding their diagnosis.
Key facts
- Study ID
- NCT00367900
- Run by
- National Institute of Environmental Health Sciences (NIEHS)
- People needed
- 3100
- Starts
- 2006-08-21
- Expected to finish
- 2014-06-04
- Last updated by the study team
- 2021-03-18
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may not qualify if…
- No children are included.
- The analytic sample includes all participants who respond to the follow-up questionnaires and have non-missing values on the baseline surveys. Participants who reported PD before exposure assessment may be excluded from the analyses.
Where it is running
- NIEHS, Research Triangle Park — Research Triangle Park, North Carolina, United States
Full record on ClinicalTrials.gov
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