Ketoprofen Topical Patch, 20% in the Treatment of Pain Associated With Osteoarthritis Flare of the Knee

Completed · Phase 3

Conditions studied: Osteoarthritis

In brief

The purpose of this study is to evaluate the effect of a ketoprofen topical patch on the pain associated with Osteoarthritis Flare of the Knee.

Key facts

Study ID

NCT00365586

Run by

APR Applied Pharma Research s.a.

People needed

300

Starts

2006-08-01

Expected to finish

2007-05-01

Last updated by the study team

2020-02-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males or females 18 years of age or older
• Diagnosis of osteoarthritis of the knee (unilateral or bilateral)
• Meet pain entry criteria
• Willing to discontinue use of all analgesic medications (including over-the-counter [OTC] analgesics) except those provided as the study treatment and rescue medication specifically for study purposes.

You may not qualify if…

• Positive urine pregnancy test, pregnant or lactating.
• Have fibromyalgia, inflammatory arthritis, gout, pseudo-gout or Paget's disease
• Have any other type of clinically significant joint disease or have had joint replacement surgery at the index knee
• Have received either a corticosteroid injection in the 4 weeks preceding the screening visit or hyaluronic acid within 6 months of the screening visit
• Have a history or physical examination finding that is incompatible with safe participation in the study or study product use
• Are taking medications or other substances contraindicated due to the nature of the study medication or the potential for drug interactions.
• Have significant renal or hepatic impairment
• Are taking a sleep medication at a dose that has not been stable for at least 3 months

Where it is running

• PPD — Austin, Texas, United States

Full record on ClinicalTrials.gov

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