Efficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior Chemotherapy

Completed · Phase 3

Conditions studied: Non Small Cell Lung Cancer

In brief

To determine if ZD6474 a new investigational drug, is effective in treating Non Small Lung Cancer and if so, how it compares with another type of anti cancer therapy chemotherapy, Erlotinib

Key facts

Study ID

NCT00364351

Run by

Genzyme, a Sanofi Company

People needed

1574

Starts

2006-08-01

Expected to finish

2016-11-01

Last updated by the study team

2018-01-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Confirmed locally advanced or metastatic NSCLC
• Failure of at least one but not more than two prior chemotherapy regimens

You may not qualify if…

• Prior treatment with erlotinib (Tarceva), gefitinib (IRESSA), sunitinib (Sutent), sorafenib (Nexavar)
• Chemotherapy or other type of anti cancer therapy within 4 weeks of study start

Where it is running

• Research Site — Los Angeles, California, United States
• Research Site — Santa Rosa, California, United States
• Research Site — Boynton Beach, Florida, United States
• Research Site — Fort Myers, Florida, United States
• Research Site — Jacksonville, Florida, United States
• Research Site — Port Saint Lucie, Florida, United States
• Research Site — Wichita, Kansas, United States
• Research Site — Lexington, Kentucky, United States
• Research Site — Louisville, Kentucky, United States
• Research Site — Metairie, Louisiana, United States
• Research Site — Baltimore, Maryland, United States
• Research Site — Columbia, Missouri, United States
• Research Site — St Louis, Missouri, United States
• Research Site — Latham, New York, United States
• Research Site — Hickory, North Carolina, United States
• Research Site — Canton, Ohio, United States
• Research Site — Cincinnati, Ohio, United States
• Research Site — Greenville, South Carolina, United States
• Research Site — Chattanooga, Tennessee, United States
• Research Site — Nashville, Tennessee, United States
• Research Site — Amarillo, Texas, United States
• Research Site — Garland, Texas, United States
• Research Site — Webster, Texas, United States
• Research Site — Fairfax, Virginia, United States
• Research Site — Berkeley, California, United States

Full record on ClinicalTrials.gov

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