Treatment of Olfactory Dysfunction in Seasonal Allergic Rhinitis

Stopped early · Phase 4 · Has a placebo group

Conditions studied: Seasonal Allergic Rhinitis

In brief

People with allergies frequently complain of a loss or reduction in the sense of smell. In this study, the investigators propose to perform a randomized, double blind, placebo controlled parallel study of subjects with nasal allergies and decreased smell to determine the effect of a treatment for allergies on the sense of smell.

Key facts

Study ID

NCT00361439

Run by

University of Chicago

People needed

17

Starts

2006-08-01

Expected to finish

2008-09-01

Last updated by the study team

2014-02-28

Who can join

Age: 18 and older, up to 59. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Males and females between 18 and 59 years of age.
• Seasonal allergic rhinitis by clinical history, with symptoms of impaired olfaction.
• Positive skin or RAST test to allergen.
• Symptoms of olfactory dysfunction.
• No significant history of chronic sinusitis.

You may not qualify if…

• Women of childbearing potential not using the contraception method(s) (Birth control pills, depo Provera, double barrier) as well as women who are breastfeeding.
• Patients with severe medical condition(s) that in the view of the investigator prohibits participation in the study (heart, lung, kidney, neurological, oncologic or liver disease).
• Use of any other investigational agent in the last 30 days.
• Absence of olfactory or nasal symptoms.
• Use of medications that may affect olfaction.
• Medical conditions that may affect olfaction.
• Smoking.
• URI at the time of screening.

Where it is running

• University of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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