Donor Mesenchymal Stem Cell Infusion in Treating Patients With Acute or Chronic Graft-Versus-Host Disease After Undergoing a Donor Stem Cell Transplant

Completed · Phase 1

Conditions studied: Cancer

In brief

RATIONALE: Donor mesenchymal stem cell infusion may be an effective treatment for acute or chronic graft-versus-host disease caused by a donor stem cell transplant. PURPOSE: This phase I trial is studying the side effects and best dose of donor mesenchymal stem cells in treating patients with acute or chronic graft-versus-host disease after undergoing a donor stem cell transplant.

Key facts

Study ID

NCT00361049

Run by

Case Comprehensive Cancer Center

People needed

49

Starts

2004-09-01

Expected to finish

2010-11-01

Last updated by the study team

2010-11-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Geauga Regional Hospital — Cleveland, Ohio, United States
• Lake/University Ireland Cancer Center — Cleveland, Ohio, United States
• Ireland Cancer Center at University Hosptials Case Medical Center, Case Comprehensive Cancer Center — Cleveland, Ohio, United States
• University Suburban Health Center — Cleveland, Ohio, United States
• UHHS Chagrin Highlands Medical Center — Cleveland, Ohio, United States
• Southwest General Health Center — Cleveland, Ohio, United States
• UHHS Westlake Medical Center — Cleveland, Ohio, United States
• Mercy Cancer Center at Mercy Medical Center — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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