Does a Migraine Medication Decrease Rotational Motion Sickness in People Suffering From Migraines?

Completed · Not applicable · Has a placebo group

Conditions studied: Migraine

In brief

The purpose of this study is to determine if Rizatriptan, a migraine medication, lowers motion sickness in migraine sufferers.

Key facts

Study ID

NCT00360282

Run by

University of Pittsburgh

People needed

36

Starts

2006-08-01

Expected to finish

2010-03-01

Last updated by the study team

2014-12-08

Who can join

Age: 21 and older, up to 45. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• History of motion sickness
• Currently suffering from migraines with at least 2 episodes during the previous 12 months
• Previous use and tolerance to triptans

You may not qualify if…

• Current tobacco user
• History of or current hypertension, cardiac disease, arrhythmia, hypercholesterolemia, hemiplegic/basilar migraine, stroke, diabetes, vascular disease or kidney disease
• Family history of early myocardial infarction (first-degree relative < 45 years old at time of event)
• Constant dizziness or constant vestibular symptoms
• History of ear, nose and throat (ENT) disease, e.g. Meniere's disease
• Current treatment with propranolol or medications that would preclude use of a triptan(e.g. ergotamine)
• Major vestibular abnormality found on screening
• Testing positive on over-the-counter pregnancy test
• Taken an Monamine Oxidase (MAO) inhibitor within two weeks of testing
• Allergy or intolerance to gelatin
• Corrected visual acuity of > 20/40 O.U.
• Women who are pregnant or breastfeeding

Where it is running

• University of Pittsburgh — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.