Sildenafil Study to Treat Idiopathic Pulmonary Fibrosis

Completed · Phase 2 · Has a placebo group

Conditions studied: Alveolitis, Fibrosing, Fibrosis, Pulmonary, Hypertension, Pulmonary

In brief

Medicines that decrease blood pressure in the lungs may help idiopathic pulmonary fibrosis (IPF) patients function better. This study will test whether sildenafil improves the ability to exercise in patients with pulmonary fibrosis of unknown cause.

Key facts

Study ID

NCT00359736

Run by

VA Office of Research and Development

People needed

29

Starts

2006-07-01

Expected to finish

2009-06-01

Last updated by the study team

2017-11-01

Who can join

Age: 40 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Clinical diagnosis of IPF
• 40-85 years of age
• 6-minute walk distance 150-500 m
• FVC 40-90% predicted
• DLCO 30-90% predicted

You may not qualify if…

• Severe pulmonary hypertension
• Severe heart failure
• FEV1/FVC < 0.7

Where it is running

• VA Medical Center, Miami — Miami, Florida, United States

Full record on ClinicalTrials.gov

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