Immune Responses to Antigens in Non-infectious Eye Inflammatory Diseases

Completed

Conditions studied: Eye Diseases

In brief

This study will collect blood samples from patients with non-infectious eye inflammatory diseases a spectrum of eye disorders that can produce sight-threatening vision loss. The blood will be analyzed for substances that may provide a better understanding of the nature of these disorders, possibly leading to improved treatments. Treatment is not offered under this protocol. Patients 6 years of age and older with an eye inflammatory disease, including non-infectious uveitis, ocular cicatricial pemphigoid, non-infectious scleritis, episcleritis, Stevens Johnson syndrome, Moorens ulcer, peripheral ulcerative keratitis and keratoconjunctivitis sicca, may be eligible for this study. Patients may or may not currently be participating in a treatment trial. Participants will have blood drawn through a needle in an arm vein. More samples may be collected if patients enrolled in another study are scheduled for additional visits. No more than 4 teaspoonfuls of blood will be collected at any one time.

Key facts

Study ID

NCT00357071

Run by

National Eye Institute (NEI)

People needed

219

Starts

2003-04-07

Expected to finish

2018-07-24

Last updated by the study team

2018-07-26

Who can join

Age: 6 and older. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• The presence of non-ocular inflammatory disease.
• Unwilling or unable to provide a blood sample.

Where it is running

• National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States

Full record on ClinicalTrials.gov

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