Ramipril and Hydrochlorothiazide Alone and in Combination for the Treatment of Essential Hypertension

Completed · Phase 3

Conditions studied: Hypertension, Blood Pressure, High

In brief

The purpose of this study is to determine if there is greater blood pressure reduction using ramipril or hydrochlorothiazide alone or ramipril and hydrochlorothiazide together.

Key facts

Study ID

NCT00355589

Run by

Pfizer

Starts

2006-07-01

Expected to finish

2007-03-01

Last updated by the study team

2012-10-10

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Previously diagnosed, or newly diagnosed essential hypertension. Blood pressure must be within a minimum and maximum range prior to drug treatment.

You may not qualify if…

• Inability to discontinue all prior antihypertensive medications
• Heart failure
• History of stroke, myocardial infarction, or chest pain within 3 years, or an abnormal heart rhythm
• Liver or kidney disease
• Certain drugs used to treat other conditions like an enlarged prostate gland, or arthritis
• Allergy or reactions to certain medications used to treat high blood pressure
• Other protocol-defined inclusion and exclusion criteria apply.

Where it is running

• Clinical Research Associates — Huntsville, Alabama, United States
• Pulmonary Associates — Glendale, Arizona, United States
• Impact Clinical Trials — Beverly Hills, California, United States
• Lovelace Scientific Resources, Inc. — Beverly Hills, California, United States
• Associated Pharmaceutical Research Center, Inc. — Buena Park, California, United States
• Marin Endocrine Care and Research — Greenbrae, California, United States
• Memorial Research Medical Clinic — Long Beach, California, United States
• The Intermed Group; Samaritan Medical Tower — Los Angeles, California, United States
• National Research Institute — Los Angeles, California, United States
• Clinical Trials Research — Roseville, California, United States
• Bayview Research Group — Studio City, California, United States
• Viking Clinical Research — Temecula, California, United States
• University of Connecticut Health Center — Farmington, Connecticut, United States
• Clinical Research of West Florida, Inc. — Clearwater, Florida, United States
• Clinical Research of South Florida — Coral Gables, Florida, United States
• University Clinical Research Deland, Inc. — DeLand, Florida, United States
• South Florida Clinical Research Center — Hollywood, Florida, United States
• Innovative Research of West Florida — Largo, Florida, United States
• International Research Associates, LLC — Miami, Florida, United States
• Lifespan Research Foundation — Miami, Florida, United States
• Sun Coast Clinical Research — New Port Richey, Florida, United States
• Renstar Medical Research — Ocala, Florida, United States
• Suncoast Clinical Research, Inc. — Palm Harbor, Florida, United States
• University Clinical Research, Inc. — Pembroke Pines, Florida, United States
• Cahaba Research Inc. — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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