Imatinib Mesylate and Hydroxyurea in Treating Patients With Recurrent or Progressive Meningioma
Completed · Phase 2
Conditions studied: Glioblastoma, Gliosarcoma
In brief
RATIONALE: Imatinib mesylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as hydroxyurea, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving imatinib mesylate together with hydroxyurea may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving imatinib mesylate together with hydroxyurea works in treating patients with recurrent or progressive meningioma.
Key facts
- Study ID
- NCT00354913
- Run by
- Duke University
- People needed
- 21
- Starts
- 2005-05-01
- Expected to finish
- 2010-10-01
- Last updated by the study team
- 2013-01-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Duke Cancer Institute — Durham, North Carolina, United States
Full record on ClinicalTrials.gov
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