Investigating Cytokine Genes of Stem Cell Donors

Completed

Conditions studied: Stem Cell Transplantation

In brief

This study seeks to investigate the factors that may account for the differences in the way a stem cell recipient s immune system works after a transplant. It will focus on cytokine genes, which give specific instructions to the genes and which may influence immune system response. More specifically, the purpose of the study is to find out how gene polymorphisms (gene variations among the population) affect the success or failure of a stem cell transplant. Study participants will have donated blood for a stem cell transplant. They will be asked to give consent for NIH personnel to run special tests on these blood samples, which will have been placed in storage. It is hoped that blood samples will be studied from 600 stem cell donors.

Key facts

Study ID

NCT00353821

Run by

National Heart, Lung, and Blood Institute (NHLBI)

People needed

24

Starts

2003-06-05

Expected to finish

2018-03-02

Last updated by the study team

2019-12-12

Who can join

Age: 2 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• Subjects unable to comprehend the investigational nature of the laboratory research.

Where it is running

• National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States

Full record on ClinicalTrials.gov

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