Experience of Having Chronic Graft-Versus-Host Disease

Completed

Conditions studied: Graft-Versus-Host Disease

In brief

Primary Objectives: 1. To explore the experience of chronic graft-versus-host disease (cGVHD) following allogeneic blood or marrow transplantation from the perspective of the patient and the patient's primary family caregiver. 2. To develop and validate an instrument to measure the severity of multiple symptoms and the impact of these symptoms on daily functioning in patients who have cGVHD. Secondary Objectives: 1. To develop a detailed description of the experience of having cGVHD. 2. To develop a detailed description of the symptom experience of cGVHD to allow for development of a symptoms instrument for cGVHD. 3. To assess the understanding of questions to measure the symptoms of cGVHD in patients with various levels of education. 4. To develop a detailed description of caring for a patient with cGVHD.

Key facts

Study ID

NCT00353106

Run by

M.D. Anderson Cancer Center

People needed

187

Starts

2006-02-01

Expected to finish

2010-01-01

Last updated by the study team

2012-07-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18 years of age or older
• Ability to speak and read English
• Clinical or histological diagnosis of active cGVHD or at least 3 months post allogeneic BMT without a diagnosis of active GVHD (PATIENT ONLY)
• Identification as the single primary family caregiver by a patient with cGVHD (CAREGIVER ONLY)
• Physician or nurse with at least 5 years experience caring for patients with cGHVD (PROFESSIONAL EXPERT ONLY)
• At least one publication in the last 5 years dealing with cGVHD (PHYSICIAN PROFESSIONAL EXPERT ONLY)
• Consent to participate

You may not qualify if…

• Inability to understand the intent of the study
• Medical condition that would preclude participation in an interview lasting 30 minutes (PHASE 1 OF STUDY ONLY)
• Diagnosis of active psychosis or severe cognitive impairment
• Bone marrow or stem cell donor for patient (CAREGIVER ONLY)
• Disease for which BMT was performed not in remission (PATIENT ONLY)

Where it is running

• Roswell Park Cancer Institute — Buffalo, New York, United States
• UT MD Anderson Cancer Center — Houston, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.