Vinblastine and Carboplatin in Treating Young Patients With Newly Diagnosed or Recurrent Low-Grade Glioma
Completed · Phase 1
Conditions studied: Brain and Central Nervous System Tumors, Neurofibromatosis Type 1
In brief
RATIONALE: Drugs used in chemotherapy, such as vinblastine and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of vinblastine when given together with carboplatin in treating young patients with newly diagnosed or recurrent low-grade glioma.
Key facts
- Study ID
- NCT00352495
- Run by
- Children's Oncology Group
- People needed
- 26
- Starts
- 2006-06-01
- Expected to finish
- 2012-03-01
- Last updated by the study team
- 2014-02-13
Who can join
Age: any, up to 21. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham — Birmingham, Alabama, United States
- Children's Hospital of Orange County — Orange, California, United States
- Children's National Medical Center — Washington D.C., District of Columbia, United States
- Children's Memorial Hospital - Chicago — Chicago, Illinois, United States
- Indiana University Melvin and Bren Simon Cancer Center — Indianapolis, Indiana, United States
- Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute — Boston, Massachusetts, United States
- C.S. Mott Children's Hospital at University of Michigan Medical Center — Ann Arbor, Michigan, United States
- Masonic Cancer Center at University of Minnesota — Minneapolis, Minnesota, United States
- Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis — St Louis, Missouri, United States
- Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center — New York, New York, United States
- SUNY Upstate Medical University Hospital — Syracuse, New York, United States
- Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States
- Oregon Health and Science University Cancer Institute — Portland, Oregon, United States
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
- Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania, United States
- St. Jude Children's Research Hospital — Memphis, Tennessee, United States
- Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas — Dallas, Texas, United States
- Baylor University Medical Center - Houston — Houston, Texas, United States
- Children's Hospital and Regional Medical Center - Seattle — Seattle, Washington, United States
- Hospital for Sick Children — Toronto, Ontario, Canada
- Hopital Sainte Justine — Montreal, Quebec, Canada
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.