The Use of GnRH Agonist Trigger in the Prevention of OHSS

Completed · Phase 4

Conditions studied: Ovarian Hyperstimulation Syndrome

In brief

To compare the incidence of ovarian hyperstimulation syndrome (OHSS) and implantation rate between high responder patients using Gonadotropin releasing GnRH) agonist or human chorionic gonadotropin (hCG) to trigger final oocyte maturation.

Key facts

Study ID

NCT00349258

Run by

University of Connecticut

People needed

66

Starts

2004-08-01

Expected to finish

2006-05-01

Last updated by the study team

2006-07-06

Who can join

Age: 20 and older, up to 39. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• age 20-39
• normal early follicular phase serum FSH (≤10.0 IU/l)
• patients with either PCOS or PCOM undergoing their first cycle of IVF or patients with high response in a previous IVF cycle.

You may not qualify if…

• Hypogonadotropic hypogonadism

Where it is running

• Center for Advanced Reproductive Services, UCHC — Farmington, Connecticut, United States

Full record on ClinicalTrials.gov

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