Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin C

Completed · Phase 4

Conditions studied: Glaucoma

In brief

A clinical trial to establish the long term response of using intraoperative 5-fluorouracil (5-FU) versus mitomycin C (MMC) in trabeculectomy glaucoma surgery. Antiproliferative agents such as 5-fluorouracil and Mitomycin C have been used extensively in trabeculectomy surgery to improve the success of the surgery and prevent further visual loss and blindness in glaucoma patients.

Key facts

Study ID

NCT00346489

Run by

Indiana University

People needed

70

Starts

2004-09-01

Expected to finish

2007-08-01

Last updated by the study team

2007-12-27

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Only patients deemed successful as 36 months will be included. These patients will have participated in the randomized prospective study trial comparing intraoperative 5-FU and mitomycin C in primary trabeculectomy.

You may not qualify if…

• Only patients deemed successful as 36 months will be included. These patients will have participated in the randomized prospective study trial comparing intraoperative 5-FU and mitomycin C in primary trabeculectomy.

Where it is running

• University Hospital and Outpatient Center — Indianapolis, Indiana, United States
• IU Eye at Carmel — Indianapolis, Indiana, United States

Full record on ClinicalTrials.gov

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