Isolation and Characterization of Mammary Stem Cells
Completed
Conditions studied: Stem Cells
In brief
Background: * Cancer stem cells in breast cancer have been identified as a small population of tumor cells whose self-renewal mechanism is highly deregulated. This deregulation seems to be necessary for cancer to develop. * These cells can be identified by certain surface markers that overlap with markers associated with normal embryonic stem cells. Objective: To isolate tumor stem cells using the same methods generally used to isolate human embryonic stem cells. Eligibility: * Tissue samples will be obtained from the human cooperative network. * Samples will include normal tissues from individuals who have no opportunistic diseases and from individuals with cancer. Design: Breast cancer stem cells will be isolated, grown in the laboratory and characterized.
Key facts
- Study ID
- NCT00340392
- Run by
- National Cancer Institute (NCI)
- People needed
- 400
- Starts
- 2006-04-07
- Expected to finish
- 2011-03-23
- Last updated by the study team
- 2017-07-02
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may not qualify if…
- The tissue samples will come from the human cooperative tissue network and we are asking for normal samples from individuals who don't have any opportunistic diseases.
Where it is running
- National Cancer Institute (NCI), 9000 Rockville Pike — Bethesda, Maryland, United States
Full record on ClinicalTrials.gov
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