Treatment of the Human Anti-TNF Monoclonal Antibody Adalimumab in Moderate to Severe Crohn's Disease With Previous Exposure to Infliximab (CHOICE)

Completed · Phase 3

Conditions studied: Crohn's Disease

In brief

The primary objective of this study is to make adalimumab available to patients suffering from moderately to severely active Crohn's Disease who have failed to respond to, lost response to, or are intolerant to infliximab, and to evaluate safety

Key facts

Study ID

NCT00338650

Run by

Abbott

People needed

1000

Starts

2006-06-01

Expected to finish

2007-05-01

Last updated by the study team

2007-11-29

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient diagnosed with moderate to severe Crohn's Disease.
• Failed prior infliximab therapy.
• Patient is judged to be in generally good health as determined by the principal investigator.

You may not qualify if…

• Previous treatment with adalimumab.
• Patient considered by the investigator, for any reason, to be an unsuitable candidate

Where it is running

• Study site — Jonesboro, Arkansas, United States
• Study site — Little Rock, Arkansas, United States
• Study site — Roseville, California, United States
• Study site — San Francisco, California, United States
• Study site — Englewood, Colorado, United States
• Study site — Wheat Ridge, Colorado, United States
• Study site — Bridgeport, Connecticut, United States
• Study site — Hamden, Connecticut, United States
• Study site — Clearwater, Florida, United States
• Study site — Gainesville, Florida, United States
• Study site — Gainesville, Florida, United States
• Study site — Hollywood, Florida, United States
• Study site — Jacksonville, Florida, United States
• Study site — Jacksonville, Florida, United States
• Study site — Miami, Florida, United States
• Study site — North Miami Beach, Florida, United States
• Study site — Winter Park, Florida, United States
• Study site — Atlanta, Georgia, United States
• Study site — Atlanta, Georgia, United States
• Study site — Atlanta, Georgia, United States
• Study site — Conyers, Georgia, United States
• Study site — Marietta, Georgia, United States
• Study site — Savannah, Georgia, United States
• Study site — Arlington Heights, Illinois, United States
• Study site — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.