Randomised Study to Compare the Efficacy of AZD6244 vs TMZ

Completed · Phase 2

Conditions studied: Melanoma

In brief

The primary purpose of this study is to compare the efficacy of AZD6244 (ARRY-142886) with temozolomide in patients with advanced melanoma

Key facts

Study ID

NCT00338130

Run by

AstraZeneca

People needed

239

Starts

2006-07-01

Expected to finish

2013-07-01

Last updated by the study team

2014-08-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed with late stage malignant melanoma
• Aged 18 or over
• Female patients must be post-menopausal or with negative urine pregnancy test if pre-menopausal

You may not qualify if…

• Any previous radiotherapy or chemotherapy (palliative radiotherapy is acceptable)
• Participation in any other trial with an investigational product within the previous 30 days

Where it is running

• Research Site — Santa Monica, California, United States
• Research Site — Aurora, Colorado, United States
• Research Site — Miami Beach, Florida, United States
• Research Site — Niles, Illinois, United States
• Research Site — Boston, Massachusetts, United States
• Research Site — Buffalo, New York, United States
• Research Site — New York, New York, United States
• Research Site — Oklahoma City, Oklahoma, United States
• Research Site — Pittsburgh, Pennsylvania, United States
• Research Site — Nashville, Tennessee, United States
• Research Site — Ciudad de Buenos Aires, Argentina
• Research Site — Vicente López, Argentina
• Research Site — Heidelberg, Australia
• Research Site — Nedlands, Australia
• Research Site — Waratah, Australia
• Research Site — Sankt Pölten, Austria
• Research Site — Vienna, Austria
• Research Site — Belo Horizonte, Brazil
• Research Site — Curitiba, Brazil
• Research Site — Goiânia, Brazil
• Research Site — Porto Alegre, Brazil
• Research Site — Salvador, Brazil
• Research Site — São Paulo, Brazil
• Research Site — Oshawa, Ontario, Canada
• Research Site — Montreal, Quebec, Canada

Full record on ClinicalTrials.gov

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