A Phase 2 Evaluation of Anti-VEGF Therapy for Diabetic Macular Edema: Bevacizumab (Avastin)
Completed · Phase 2 · Has a placebo group
Conditions studied: Diabetic Retinopathy
In brief
This study will provide preliminary data on the dose and dose interval related effects of intravitreally administered Avastin on retinal thickness and visual acuity in subjects with Diabetic Macular Edema (DME) to aid in planning a phase 3 trial. In addition, this study will provide preliminary data on the safety of intravitreally administered Avastin in subjects with DME.
Key facts
- Study ID
- NCT00336323
- Run by
- Jaeb Center for Health Research
- People needed
- 121
- Starts
- 2006-06-01
- Expected to finish
- 2008-02-01
- Last updated by the study team
- 2016-08-26
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Loma Linda University Health Care, Dept. of Ophthalmology — Loma Linda, California, United States
- Southern California Desert Retina Consultants, MC — Palm Springs, California, United States
- California Retina Consultants — Santa Barbara, California, United States
- Bay Area Retina Associates — Walnut Creek, California, United States
- Retina Vitreous Consultants — Fort Lauderdale, Florida, United States
- Central Florida Retina Institute — Lakeland, Florida, United States
- Southeast Retina Center, P.C. — Augusta, Georgia, United States
- Illinois Retina Associates — Joliet, Illinois, United States
- Raj K. Maturi, M.D., P.C. — Indianapolis, Indiana, United States
- American Eye Institute — New Albany, Indiana, United States
- Retina and Vitreous Associates of Kentucky — Lexington, Kentucky, United States
- Paducah Retinal Center — Paducah, Kentucky, United States
- Maine Vitreoretinal Consultants — Bangor, Maine, United States
- Elman Retina Group, P.A. — Baltimore, Maryland, United States
- Retina Consultants of Delmarva, P.A. — Salisbury, Maryland, United States
- Ophthalmic Consultants of Boston — Boston, Massachusetts, United States
- Joslin Diabetes Center — Boston, Massachusetts, United States
- Retina Center, PA — Minneapolis, Minnesota, United States
- Charlotte Eye, Ear, Nose and Throat Assoc., PA — Charlotte, North Carolina, United States
- Wake Forest University Eye Center — Winston-Salem, North Carolina, United States
- Retina Associates of Cleveland, Inc. — Beachwood, Ohio, United States
- Retina Northwest, PC — Portland, Oregon, United States
- Casey Eye Institute — Portland, Oregon, United States
- Penn State College of Medicine — Hershey, Pennsylvania, United States
- Retina Consultants — Providence, Rhode Island, United States
Full record on ClinicalTrials.gov
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