Cellular and Molecular Events During Treatment of Actinic Keratosis With Imiquimod 5% Cream

Completed · Phase 2 · Has a placebo group

Conditions studied: Actinic Keratosis

In brief

Treatment of actinic keratosis with imiquimod cream is expected to cause changes in the genes that are turned on, and turned off, by skin cells. Some of the drug induced changes in skin cells should also be visible using a special microscope. This study examines both types of changes.

Key facts

Study ID

NCT00335179

Run by

Graceway Pharmaceuticals, LLC

People needed

17

Starts

2003-01-01

Expected to finish

2003-07-01

Last updated by the study team

2010-07-23

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Have actinic keratoses on balding scalp
• Discontinuation of tanning bed use
• Discontinuation of moisturizers
• Avoidance of retinol products

You may not qualify if…

• Uncontrolled, clinically significant medical condition
• Dermatologic disease other than actinic keratosis in treatment area

Where it is running

• Loma Linda University Medical Center — Loma Linda, California, United States

Full record on ClinicalTrials.gov

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