Intensity-Modulated Radiation Therapy to the Pelvis With or Without Chemotherapy in Treating Patients With Endometrial Cancer or Cervical Cancer That Has Been Removed By Surgery
Completed · Phase 2
Conditions studied: Cervical Cancer, Endometrial Cancer
In brief
RATIONALE: Specialized radiation therapy (RT), such as intensity-modulated radiation therapy (IMRT), that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving intensity-modulated radiation therapy to the pelvis with or without chemotherapy after surgery may kill any tumor cells that remain after surgery. PURPOSE: This phase II trial is studying how well intensity-modulated radiation therapy to the pelvis with or without chemotherapy works in treating patients with endometrial cancer or cervical cancer that has been removed by surgery.
Key facts
- Study ID
- NCT00331760
- Run by
- Radiation Therapy Oncology Group
- People needed
- 106
- Starts
- 2006-03-01
- Expected to finish
- 2016-12-01
- Last updated by the study team
- 2019-02-26
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
Where it is running
- Radiation Oncology Centers - Cameron Park — Cameron Park, California, United States
- Mercy Cancer Center at Mercy San Juan Medical Center — Carmichael, California, United States
- East Bay Radiation Oncology Center — Castro Valley, California, United States
- Eden Medical Center — Castro Valley, California, United States
- Valley Medical Oncology Consultants - Castro Valley — Castro Valley, California, United States
- City of Hope Comprehensive Cancer Center — Duarte, California, United States
- Valley Medical Oncology — Fremont, California, United States
- Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
- Highland General Hospital — Oakland, California, United States
- Alta Bates Summit Medical Center - Summit Campus — Oakland, California, United States
- Bay Area Breast Surgeons, Incorporated — Oakland, California, United States
- CCOP - Bay Area Tumor Institute — Oakland, California, United States
- Larry G Strieff MD Medical Corporation — Oakland, California, United States
- Tom K Lee, Incorporated — Oakland, California, United States
- Valley Care Medical Center — Pleasanton, California, United States
- Valley Medical Oncology Consultants - Pleasanton — Pleasanton, California, United States
- Radiation Oncology Center - Roseville — Roseville, California, United States
- Radiological Associates of Sacramento Medical Group, Incorporated — Sacramento, California, United States
- Mercy General Hospital — Sacramento, California, United States
- Veterans Affairs Medical Center - San Diego — San Diego, California, United States
- UCSF Helen Diller Family Comprehensive Cancer Center — San Francisco, California, United States
- Doctors Medical Center - San Pablo Campus — San Pablo, California, United States
- Solano Radiation Oncology Center — Vacaville, California, United States
- Tunnell Cancer Center at Beebe Medical Center — Lewes, Delaware, United States
- Auburn Radiation Oncology — Auburn, California, United States
Full record on ClinicalTrials.gov
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