B-type Natriuretic Peptide in the Non-Cardiac Pediatric Patient
Completed
Conditions studied: Heart Diseases
In brief
B-type Natriuretic Peptide (BNP) is a hormone that is made by the pumping chambers of the heart. The BNP level can be measured by a blood test and is used as a marker for heart problems in adults. Deciding if a child has a heart problem or a lung problem can be very difficult, especially in infants. Several studies have demonstrated that BNP levels are elevated when children have heart disease. The overall goal of the study is to be able to prove that obtaining BNP levels in pediatric patients can be used to identify heart problems. We already know that kids with heart problems have high BNP levels (\>200pg/ml). We need to prove that children who come to the Emergency Department for non-cardiac problems still have normal BNP levels (\<100pg/ml, slightly higher in the newborn population). This will be done by comparing BNP levels with the final diagnosis made by the ED physician.
Key facts
- Study ID
- NCT00330811
- Run by
- Emory University
- People needed
- 87
- Starts
- 2006-04-01
- Expected to finish
- 2007-05-01
- Last updated by the study team
- 2016-12-02
Who can join
Age: 0 and older, up to 5. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Any child presenting to the pediatric ED at Children's Healthcare of Atlanta (CHOA)at Egleston undergoing evaluation for respiratory and/or infectious disease.
- Patient age is less than 6 years old.
- Patients having venipuncture for lab studies as a part of the ED admission.
- Informed consent being obtained from the legal guardians.
You may not qualify if…
- Patients with known congenital or acquired heart disease.
- Patients with previously diagnosed systemic disease such as malignancy, HIV, cystic fibrosis, organ transplant recipients.
- Patients that will not be having venipuncture for lab studies as a part of the ED admission.
- Trauma patients or those presenting with broken bones, dog bites, etc. (non-infectious presentation.)
Where it is running
- Children's Healthcare of Atlanta — Atlanta, Georgia, United States
Full record on ClinicalTrials.gov
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