An Open-Label Trial of Memantine in the Treatment of Binge Eating Disorder

Completed · Phase 4

Conditions studied: Binge Eating Disorder

In brief

We hypothesize that memantine may be a safe and effective treatment for moderate to severe binge eating disorder associated with obesity. During this 12-week, open-label, outpatient study, male and female subjects between the ages of 18 and 65 years who have moderate to severe binge eating disorder and are obese will be treated with open-label memantine. Following this 12-week treatment phase, subjects may be eligible to continue into an extension phase which will last an additional 12 weeks. During the extension phase subjects will continue open-label memantine treatment.

Key facts

Study ID

NCT00330655

Run by

Mclean Hospital

People needed

15

Starts

2006-05-01

Expected to finish

2007-07-01

Last updated by the study team

2007-08-14

Who can join

Age: 16 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects may be male or female, 18-65 years old
• Diagnosis of binge eating disorder
• Subjects must have 3 or more binge days per week for the two weeks prior to the start of the study
• Subjects must have a BMI between 30 and 50 kg/m2

You may not qualify if…

• Current or lifetime history of schizophrenia, other psychotic disorder, or bipolar disorder
• Subjects with a history of a personality disorder
• Subjects with clinically significant depression
• Subjects with substance use of dependence
• Subjects who are pregnant or lactating
• Subjects with a serious medical condition

Where it is running

• McLean Hospital — Belmont, Massachusetts, United States

Full record on ClinicalTrials.gov

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