Zoledronate in Preventing Osteoporosis and Bone Fractures in Patients With Locally Advanced Nonmetastatic Prostate Cancer Undergoing Radiation Therapy and Hormone Therapy
Completed · Phase 3
Conditions studied: Osteoporosis, Prostate Cancer
In brief
RATIONALE: Zoledronate may prevent bone loss in patients with prostate cancer undergoing radiation therapy and hormone therapy. It is not yet known whether zoledronate is more effective than calcium and vitamin D alone in preventing osteoporosis and bone fractures in patients with prostate cancer. PURPOSE: This randomized phase III trial is studying zoledronate to see how well it works compared to calcium and vitamin D alone in preventing osteoporosis and bone fractures in patients with locally advanced nonmetastatic prostate cancer undergoing radiation therapy and hormone therapy.
Key facts
- Study ID
- NCT00329797
- Run by
- Radiation Therapy Oncology Group
- People needed
- 109
- Starts
- 2006-03-01
- Expected to finish
- 2014-11-01
- Last updated by the study team
- 2017-11-29
Who can join
Age: 18 and older. Sex: male. Healthy volunteers: not accepted.
Where it is running
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center — Pomona, California, United States
- Radiation Oncology Center - Roseville — Roseville, California, United States
- Radiological Associates of Sacramento Medical Group, Incorporated — Sacramento, California, United States
- Penrose Cancer Center at Penrose Hospital — Colorado Springs, Colorado, United States
- St. Mary - Corwin Regional Medical Center — Pueblo, Colorado, United States
- Northeast Georgia Medical Center — Gainesville, Georgia, United States
- Saint Anthony's Hospital at Saint Anthony's Health Center — Alton, Illinois, United States
- Northwest Community Hospital — Arlington Heights, Illinois, United States
- Ingalls Cancer Care Center at Ingalls Memorial Hospital — Harvey, Illinois, United States
- Saint James Hospital and Health Centers Comprehensive Cancer Institute - Olympia Fields — Olympia Fields, Illinois, United States
- CCOP - Carle Cancer Center — Urbana, Illinois, United States
- Center for Cancer Care at Goshen General Hospital — Goshen, Indiana, United States
- Methodist Cancer Center at Methodist Hospital — Indianapolis, Indiana, United States
- Lucille P. Markey Cancer Center at University of Kentucky — Lexington, Kentucky, United States
- St. Agnes Hospital Cancer Center — Baltimore, Maryland, United States
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland, United States
- Barbara Ann Karmanos Cancer Institute — Detroit, Michigan, United States
- Josephine Ford Cancer Center at Henry Ford Hospital — Detroit, Michigan, United States
- West Michigan Cancer Center — Kalamazoo, Michigan, United States
- CentraCare Clinic - River Campus — Saint Cloud, Minnesota, United States
- Coborn Cancer Center — Saint Cloud, Minnesota, United States
- Southeast Missouri Regional Cancer Center at Southeast Missouri Hospital — Cape Girardeau, Missouri, United States
- CCOP - Kansas City — Kansas City, Missouri, United States
- Enloe Cancer Center at Enloe Medical Center — Chico, California, United States
Full record on ClinicalTrials.gov
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