Using Intensity Modulated Radiation Therapy (IMRT) for Brain Metastases

Completed · Phase 1

Conditions studied: Neoplasm Metastasis

In brief

The purpose of this study is to determine if using intensity modulated radiation therapy for brain metastases is safe and will improve local control more than standard whole brain radiation therapy.

Key facts

Study ID

NCT00328575

Run by

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

People needed

10

Starts

2005-10-01

Expected to finish

2011-06-01

Last updated by the study team

2016-10-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Histologically confirmed malignancy
• 2-5 parenchymal brain metastases on magnetic resonance imaging (MRI) with a maximum size of 4 cm
• Partial resection allowed. Complete resection allowed only in patients with more than 3 lesions.
• Karnofsky Performance Status (KPS) equal to or greater than 60
• Neurologic function equal to or greater than 2

You may not qualify if…

• Recurrent brain tumors
• Major medical or psychiatric illnesses
• Metastases in brainstem, midbrain, pons, or medulla
• Patients with leukemia or lymphoma

Where it is running

• Thomas Jefferson University — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.