Gemcitabine and Carboplatin With or Without AZD2171 as First-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Completed · Phase 2
Conditions studied: Lung Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as gemcitabine and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. AZD2171 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Giving gemcitabine and carboplatin together with AZD2171 may kill more tumor cells. PURPOSE: This randomized phase II trial is studying how well giving gemcitabine and carboplatin together with AZD2171 works compared to giving gemcitabine and carboplatin without AZD2171 as first-line therapy in treating patients with stage IIIB or stage IV non-small cell lung cancer.
Key facts
- Study ID
- NCT00326599
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 101
- Starts
- 2007-06-01
- Expected to finish
- 2010-02-01
- Last updated by the study team
- 2017-03-21
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic - Jacksonville — Jacksonville, Florida, United States
- Rush-Copley Cancer Care Center — Aurora, Illinois, United States
- St. Joseph Medical Center — Bloomington, Illinois, United States
- Graham Hospital — Canton, Illinois, United States
- Memorial Hospital — Carthage, Illinois, United States
- Eureka Community Hospital — Eureka, Illinois, United States
- Galesburg Clinic, PC — Galesburg, Illinois, United States
- Galesburg Cottage Hospital — Galesburg, Illinois, United States
- Mason District Hospital — Havana, Illinois, United States
- Hopedale Medical Complex — Hopedale, Illinois, United States
- Joliet Oncology-Hematology Associates, Limited - West — Joliet, Illinois, United States
- McDonough District Hospital — Macomb, Illinois, United States
- Trinity Cancer Center at Trinity Medical Center - 7th Street Campus — Moline, Illinois, United States
- Study site — Moline, Illinois, United States
- BroMenn Regional Medical Center — Normal, Illinois, United States
- Community Cancer Center — Normal, Illinois, United States
- Community Hospital of Ottawa — Ottawa, Illinois, United States
- Oncology Hematology Associates of Central Illinois, PC - Ottawa — Ottawa, Illinois, United States
- Cancer Treatment Center at Pekin Hospital — Pekin, Illinois, United States
- Proctor Hospital — Peoria, Illinois, United States
- CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
- Oncology Hematology Associates of Central Illinois, PC - Peoria — Peoria, Illinois, United States
- Methodist Medical Center of Illinois — Peoria, Illinois, United States
- OSF St. Francis Medical Center — Peoria, Illinois, United States
- Mayo Clinic Scottsdale — Scottsdale, Arizona, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.