Plasma Brain Natriuretic Peptide Levels in Pregnancy

Completed

Conditions studied: Cardiomyopathy, Pregnancy

In brief

To evaluate the maternal blood concentrations of brain natriuretic peptide (BNP) during the second and third trimesters of a normal pregnancy. We will attempt to define a normal range for pregnancy and any outliers that may serve as markers for abnormal cardiovascular physiology.

Key facts

Study ID

NCT00324402

Run by

Oklahoma State University Center for Health Sciences

People needed

50

Starts

2006-08-01

Expected to finish

2008-06-01

Last updated by the study team

2020-10-05

Who can join

Age: 18 and older, up to 40. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• women age 18 to 40
• second trimester of pregnancy

You may not qualify if…

• known cardiac or valvular disease,
• atrial fibrillation or other arrhythmia,
• pulmonary hypertension,
• chronic hypertension,
• hypertensive disorders of pregnancy,
• morbid obesity (BMI > 40 kg/meter squared)
• history of sleep apnea
• multiple gestation
• known renal dysfunction
• medications known to affect cardiac function
• current or past abnormal echocardiogram

Where it is running

• Oklahoma State University Center for Health Sciences — Tulsa, Oklahoma, United States

Full record on ClinicalTrials.gov

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