Trial Of Erlotinib With Or Without PF-3512676 In Advanced Non Small Cell Lung Cancer

Completed · Phase 2

Conditions studied: Carcinoma, Non-Small-Cell Lung

In brief

To assess the efficacy and safety of PF-3512676 administered in combination with erlotinib in patients with advanced EGFR-positive non-small cell lung cancer after failure of at least one prior chemotherapy regimen.

Key facts

Study ID

NCT00321815

Run by

Pfizer

People needed

43

Starts

2006-08-01

Expected to finish

2010-06-01

Last updated by the study team

2010-12-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Advanced, EGFR-positive NSCLC
• ECOG Performance Status 0, 1 or 2
• Measurable disease

You may not qualify if…

• Known CNS metastasis
• Pre-existing autoimmune or antibody mediated disease

Where it is running

• Pfizer Investigational Site — Daphne, Alabama, United States
• Pfizer Investigational Site — Huntsville, Alabama, United States
• Pfizer Investigational Site — Mobile, Alabama, United States
• Pfizer Investigational Site — Corona, California, United States
• Pfizer Investigational Site — Glendora, California, United States
• Pfizer Investigational Site — Greenbrae, California, United States
• Pfizer Investigational Site — Pasadena, California, United States
• Pfizer Investigational Site — Pomona, California, United States
• Pfizer Investigational Site — Rancho Cucamonga, California, United States
• Pfizer Investigational Site — San Mateo, California, United States
• Pfizer Investigational Site — West Covina, California, United States
• Pfizer Investigational Site — Norwalk, Connecticut, United States
• Pfizer Investigational Site — Deerfield Beach, Florida, United States
• Pfizer Investigational Site — Melbourne, Florida, United States
• Pfizer Investigational Site — Miami, Florida, United States
• Pfizer Investigational Site — Munster, Indiana, United States
• Pfizer Investigational Site — Mason City, Iowa, United States
• Pfizer Investigational Site — Crestview Hills, Kentucky, United States
• Pfizer Investigational Site — Louisville, Kentucky, United States
• Pfizer Investigational Site — Bridgeton, Missouri, United States
• Pfizer Investigational Site — Chesterfield, Missouri, United States
• Pfizer Investigational Site — Kirkwood, Missouri, United States
• Pfizer Investigational Site — Somerville, New Jersey, United States
• Pfizer Investigational Site — New York, New York, United States
• Pfizer Investigational Site — Stony Brook, New York, United States

Full record on ClinicalTrials.gov

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