Study of an Oropharyngeal Aerosolized pH Probe for Diagnosing Laryngopharyngeal Reflux (LPR)

Completed

Conditions studied: Laryngopharyngeal Reflux

In brief

This study is a test of how well a new FDA-approved device is for diagnosing a condition known as laryngopharyngeal reflux (LPR). The device, which measures pH of the air in the upper throat, will be compared to several other methods for diagnosing laryngopharyngeal reflux.

Key facts

Study ID

NCT00321503

Run by

Emory University

People needed

45

Starts

2006-05-01

Expected to finish

2007-05-01

Last updated by the study team

2013-12-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Group 1 (negative control):
• RSI ≤ 13
• No history of voice or swallowing disorders
• No active voice or swallowing disorders
• No history of heartburn, regular indigestion, and no prior or current diagnosis of GERD
• Groups 2 and 3 (experimental group):
• Clinical symptoms consistent with LPR as measured by an RSI > 13.
• No other voice or swallowing pathology on clinical exam

You may not qualify if…

• Regular treatment with an H2 blocker or proton pump inhibitor (PPI)
• History of laryngeal/pharyngeal surgery
• Any planned treatment of the larynx/pharynx other than treatment for LPR
• Smoking

Where it is running

• Emory Voice Center — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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