Study of Nasal Irrigation Versus Nasal Spray for Chronic Nasal and Sinus Symptoms

Completed · Phase 4

Conditions studied: Chronic Rhinosinusitis

In brief

This study will compare nasal saline irrigation with nasal saline spray for the treatment of chronic nasal and sinus symptoms. Participants will complete a questionnaire regarding their nasal and sinus symptoms and will be randomly assigned to one of the treatment groups. Each participant will be instructed on how to perform daily nasal treatment.The subjects will complete follow-up surveys at regular intervals to assess any change in their nasal symptoms after starting nasal saline treatment. Participants may take their usual medications for sinus symptoms during their participation in the study.

Key facts

Study ID: NCT00318006
Run by: University of Michigan
People needed: 127
Starts: 2005-12-01
Expected to finish: 2006-08-01
Last updated by the study team: 2015-01-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Age > 18 years
Presence of any one of the following symptoms for > 4 days/week and > 15 days in the past 1 month:
Nasal stuffiness
Nasal congestion
Nasal dryness or crusting
Abnormal nasal discharge
Thick nasal discharge

You may not qualify if…

Functional endoscopic sinus surgery (FESS) in the last 3 months
Epistaxis in the last 3 months that required treatment
Acute illness like otitis media, laryngitis, pharyngitis, or rhinitis in the last 2 weeks
Acute attack of asthma or bronchitis in the last 2 weeks
Inability to speak or read English
Current use of any of the study medications regularly for more than a week in the last 1 month
Any history of intolerance to saline treatment (if used)

Where it is running

University of Michigan Health System — Ann Arbor, Michigan, United States

Full record on ClinicalTrials.gov

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