Use of Thalidomide in Chronic Uveitis

Stopped early · Phase 4

Conditions studied: Uveitis

In brief

This research study is for patients that have been diagnosed with chronic uveitis, a disease that causes inflammation in the eye. Patients are currently being treated with Remicade, Humira, Methotrexate and or similar chemotherapy type drugs to control this inflammation. Despite these medications, patients still have inflammation in their eyes. Patients are being asked to add an additional drug, thalidomide.

Key facts

Study ID

NCT00314665

Run by

University of Cincinnati

People needed

15

Starts

2004-01-01

Expected to finish

2006-08-01

Last updated by the study team

2007-12-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• You are being asked to take part in this research study because you have been diagnosed with chronic uveitis, a disease that causes inflammation in the eye. You are currently being treated with Remicade, Humira, Methotrexate and or similar chemotherapy type drugs to control this inflammation. Despite these medications, you still have inflammation in your eyes. You are being asked to add an additional drug, thalidomide.

You may not qualify if…

• You will not participate in this research study if any of the following apply to you:
• Pregnant
• If you are a man or woman not willing to take adequate birth control measures comply with FDA-mandated S.T.E.P.S.â program. .
• If you are a breast feeding woman
• If you have a significant peripheral neuropathy (numbness or tingling in your hands or feet)
• Have had a recent blood clot in your leg or lungs
• If you are currently receiving biphosphonates such as zoledronic acid (fosamax)

Where it is running

• University of Cincinnati Medical Center — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.