The Effect of Nebulized Albuterol on Donor Oxygenation

Completed · Phase 2 · Has a placebo group

Conditions studied: Brain Death, Organ Donor, Pulmonary Edema

In brief

The purpose of this study is to test the effectiveness of albuterol versus placebo with the following specific aims: a) Treatment of brain dead organ donors with albuterol will reduce pulmonary edema, improve donor oxygenation, and increase the number of lungs available for transplantation, b) Developing a blood test to predict the development of primary graft dysfunction in lung transplant recipients, and c) treating brain dead organ donors with albuterol will decrease markers of primary graft dysfunction and lead to improved lung transplant recipient outcomes and to higher rates of lungs suitable for transplantation.

Key facts

Study ID

NCT00310401

Run by

Vanderbilt University Medical Center

People needed

506

Starts

2007-04-01

Expected to finish

2011-06-01

Last updated by the study team

2018-03-16

Who can join

Age: 14 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Brain death
• Consent for lung donation and donor research
• Release from coroner or medical examiner

You may not qualify if…

• Age less than 14 years

Where it is running

• California Transplant Donor Network — Oakland, California, United States

Full record on ClinicalTrials.gov

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