Transcranial Magnetic Stimulation for "Voices"
Completed · Phase 2 · Has a placebo group
Conditions studied: Schizophrenia, Hallucinations
In brief
This study will determine the efficacy of MRI-guided transcranial magnetic stimulation (TMS)in reducing "voices" and other symptoms experienced by people with schizophrenia and schizoaffective disorder. In addition, the study will determine duration of improvement obtained during the course of trial participation via on-going monthly contact with study participants for up to 1 year after the trial.
Key facts
- Study ID
- NCT00308997
- Run by
- Yale University
- People needed
- 85
- Starts
- 2006-02-01
- Expected to finish
- 2012-04-01
- Last updated by the study team
- 2020-04-02
Who can join
Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Auditory hallucinations that occur at least five times per day, on average
- Diagnosis of schizophrenia or schizoaffective disorder
You may not qualify if…
- Pregnant
- History of seizure that is not drug-induced or secondary to alcohol withdrawal
- Drug or alcohol abuse within 6 weeks of study entry (prior history of drug or alcohol abuse is not an exclusion)
- Changes in antipsychotic drug dosages within 4 weeks of study entry (patients do not need to be on antipsychotic medication to be included)
- Current significant untreated or unstable medical illness (e.g., poorly controlled diabetes mellitus, severe hypertension, unstable cardiac arrhythmia)
- Inability to understand the nature of the study due to severe psychotic disorganization, mental retardation, etc.
- Significant neurological condition (e.g., traumatic brain injury, multiple sclerosis)
- Factors that would preclude an MRI scan (e.g., severe obesity, claustrophobia, certain surgical implants with metallic components, metal shavings in the eye acquired while working as machinist)
- Cardiac pacemaker
Where it is running
- Yale Psychiatric Research — New Haven, Connecticut, United States
Full record on ClinicalTrials.gov
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