Comparison Study of High Frequency Percussive Ventilation With Conventional Ventilation

Withdrawn before enrolling · Phase 2/Phase 3

Conditions studied: Respiratory Distress Syndrome, Adult, Pneumonia, Mechanical Ventilation

In brief

This study is designed to exam the effects of early management with high frequency percussive ventilation (HFPV) on patients with lung injury. Patients at risk for Acute Respiratory Distress Syndrome (ARDS) will be enrolled and randomized to one of two groups. One group will be managed with HFPV. The second group will be managed with conventional ventilation utilizing lung protective techniques. The primary endpoint of the study is rate of ventilator associated pneumonia. We hypothesized that use of HFPV in patients at risk for the development of ARDS will decrease the rate of ventilator associated pneumonia when compared to patients managed with conventional ventilation.

Key facts

Study ID

NCT00308022

Run by

University of Texas Southwestern Medical Center

People needed

0

Starts

2006-01-01

Expected to finish

2009-12-31

Last updated by the study team

2019-01-17

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• PaO2/FiO2 < 300 for less than 24 hours (Ratio of Partial pressure of oxygen to Fraction of inspired oxygen)

You may not qualify if…

• Documented Pneumonia,
• Documented Congestive Heart Failure,
• Immunosuppression,
• Enrolled in other interventional trial,

Where it is running

• Parkland Health and Hospital System — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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