Physiology of Weakness in Movement Disorders
Completed
Conditions studied: Movement Disorders
In brief
This study will compare electroencephalograph (EEG) recordings in healthy volunteers and in people with movement disorders to examine brain activity associated with the weakness. EEG records the electrical activity of the brain ("brain waves"). Healthy volunteers and patients with arm or leg weakness who are between 18 and 80 years of age may be eligible for this study. Healthy subjects are screened with a medical history, physical and neurological examinations, and a questionnaire. They must be right-handed and never have had a neurological disease or head trauma. All participants have an EEG. An elastic cap with electrodes is placed on the subject's scalp to record the brain's electrical activity. During the EEG, subjects are required to resist against a force with their arm, elbow, shoulder or leg for as long as they can. Several recordings are done with short breaks between them.
Key facts
- Study ID
- NCT00307346
- Run by
- National Institute of Neurological Disorders and Stroke (NINDS)
- People needed
- 6
- Starts
- 2006-03-23
- Expected to finish
- 2011-01-25
- Last updated by the study team
- 2017-07-02
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may not qualify if…
- Subjects (patients or volunteers) who cannot understand the instructions and consent forms of the protocol will be excluded.
- Subjects who cannot follow the instruction during the entire recording for whatever reason will be excluded.
- Patients with a documented organic central nervous system lesion may be excluded from the study. This will be discussed in detail for each individual subject at the Human Motor Control Clinic.
Where it is running
- National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States
Full record on ClinicalTrials.gov
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