Weight Management and Coping Skills Training For Patients With Knee Osteoarthritis
Completed · Not applicable
Conditions studied: Osteoarthritis
In brief
Osteoarthritis (OA) occurs when the cartilage between two bones becomes worn down, and the bones begin to rub against each other in the joint. This often leads to pain, swelling, decreased joint motion, and the formation of bone spurs (tiny growths of new bone). Being overweight increases the risk of developing OA and fastens disease progression. This study will evaluate two different programs, lifestyle behavioral weight management and pain-coping skills training, in reducing the effects of knee OA in obese individuals.
Key facts
- Study ID
- NCT00305890
- Run by
- Duke University
- People needed
- 412
- Starts
- 2004-01-01
- Expected to finish
- 2009-09-01
- Last updated by the study team
- 2018-10-25
Who can join
Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Meets the American College of Rheumatology criteria for OA
- Radiographic evidence of OA affecting one or both knees
- Complaints of chronic knee pain (pain on most days for at least 6 months prior to study entry)
- No other major weight-bearing joint affected by OA
You may not qualify if…
- Any significant medical condition or disease that would make study participation unsafe or increase the risk of a significant adverse experience during the course of the study (e.g., myocardial infarction in the 6 months prior to study entry)
- Currently involved in a regular exercise program
- An abnormal cardiac response to exercise, such as exercise-induced BT or an abnormal blood pressure response
- A body mass index (BMI) greater than 42
- A non-OA inflammatory arthropathy
- Currently using oral corticosteroids on a regular basis
- Anticipate to have a knee surgery in the next 18 months (or before the anticipated date of their study completion)
- Knee surgery (arthroscopic or knee replacement) within a year of enrollment
- Intraarticular steroid or hyaluronan knee injections in one of both knees within 3 months of enrollment
Where it is running
- Duke University Morreene Rd. Clinic — Durham, North Carolina, United States
Full record on ClinicalTrials.gov
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