Memantine Augmentation of Lamotrigine Incomplete-Response in Bipolar Depression
Completed · Phase 4 · Has a placebo group
Conditions studied: Bipolar Depression
In brief
The purpose of this study is to investigate whether addition of memantine to bipolar depression patients who have had an incomplete response to lamotrigine (Lamictal) which is frequently used to treat bipolar depression in the clinical setting. At present, memantine is approved for use in the treatment of Alzheimer's disease or dementia, but not for use for the treatment of bipolar depression. Subjects will be asked to participate because they are suffering from bipolar depression associated and have had an inadequate response to lamotrigine. Subjects will have to be on at least 100 mg per day, for at least 4 weeks.
Key facts
- Study ID
- NCT00305578
- Run by
- Indiana University
- People needed
- 29
- Starts
- 2005-08-01
- Expected to finish
- 2011-12-01
- Last updated by the study team
- 2016-07-18
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Indiana University Adult Psychiatric Clinic — Indianapolis, Indiana, United States
Full record on ClinicalTrials.gov
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