Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain

Completed · Phase 2/Phase 3

Conditions studied: Acute Pain

In brief

The purpose of this research study is to determine which opiate pain medication (morphine or hydromorphone (Dilaudid)) is more effective in the treatment of acute pain in patients presenting to the emergency department.

Key facts

Study ID

NCT00305058

Run by

Montefiore Medical Center

People needed

194

Starts

2005-07-01

Expected to finish

2007-03-01

Last updated by the study team

2018-08-20

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age greater than 65 years
• Pain with onset within 7 days
• ED attending physician's judgment that patient's pain warrants use of parenteral opioids
• Normal mental status

You may not qualify if…

• Prior use of methadone
• Use of other opioids or tramadol within past seven days
• Prior adverse reaction to morphine or hydromorphone
• Chronic pain syndrome
• Alcohol intoxication
• Systolic Blood Pressure <90 mm Hg
• Use of monoamine oxidase (MAO) inhibitors in past 30 days
• Elderly patients with a capnometry reading of greater than 46

Where it is running

• Montefiore Medical Center — The Bronx, New York, United States

Full record on ClinicalTrials.gov

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