Insulin Resistance and Breast Cancer

Completed

Conditions studied: Breast Cancer, Insulin Resistance

In brief

This study will characterize risk factors associated with breast cancer development in some patients. In particular, it will examine the role of insulin in breast cancer in patients with and without a family history of the disease. Women 30 to 70 years old who have been diagnosed with breast cancer and matched control healthy subjects with and without a family history of breast cancer may be eligible for this study. Participants undergo the following procedures: * Cancer-genetic counseling session, including family history, risk assessment, genetic testing for BRCA1 and BRCA2 (if criteria is met), interpretation of results and management options * Medical history, including questions about symptoms or diseases, reproductive history, use of oral contraceptives, body weight, exercise, lifestyle, and demographic issues * Drawing of family tree * Examination of medical records * Blood drawing for genetic and other tests * CT scan of the abdomen (approximate time \< 1 minute) * Filling out questionnaires

Key facts

Study ID
NCT00304941
Run by
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
People needed
25
Starts
2006-03-14
Expected to finish
2010-09-17
Last updated by the study team
2017-07-02

Who can join

Age: 30 and older, up to 70. Sex: female. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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