ASP-II: Ancrod Stroke Program: Ancrod (Viprinex™) for the Treatment of Acute, Ischemic Stroke

Stopped early · Phase 3 · Has a placebo group

Conditions studied: Stroke, Cerebral Ischemia, Brain Infarction

In brief

The primary purpose of this study is to determine whether a brief intravenous infusion of ancrod started within 6 hours of stroke onset improves functional outcome at 3 months.

Key facts

Study ID

NCT00300196

Run by

Neurobiological Technologies

People needed

311

Starts

2006-03-01

Expected to finish

2008-12-01

Last updated by the study team

2010-01-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Acute, ischemic stroke with first symptoms within 6 hours of beginning treatment
• Baseline NIHSS > 5

You may not qualify if…

• No intracranial, extravascular blood on CT
• Hypertension (systolic > 185; diastolic > 105)
• Baseline fibrinogen level < 100 mg/dL
• Thrombocytopenia (< 100,000 / mm3)
• Recent (< 3 days) or anticipated (< 5 days) use of a thrombolytic agent
• Recent (< 14 days) or anticipated surgery

Where it is running

• UCSF-Fresno — Fresno, California, United States
• Sherry Braheny MD - A Prof. Corporation — La Mesa, California, United States
• Mercy General Hospital — Sacramento, California, United States
• Los Robles Hospital and Medical Center — Thousand Oaks, California, United States
• Yale University School of Medicine — New Haven, Connecticut, United States
• Manatee Memorial Hospital — Bradenton, Florida, United States
• Bradenton Research Center — Bradenton, Florida, United States
• Melbourne Internal Medicine Associates — Melbourne, Florida, United States
• Collier Neurologic Specialists — Naples, Florida, United States
• Naples Community Hospital — Naples, Florida, United States
• Suncoast Neuroscience Associates — St. Petersburg, Florida, United States
• Joan Glancy Memorial Hospital — Decatur, Georgia, United States
• Joan Glancy Memorial Hospital — Duluth, Georgia, United States
• Gwinnett Medical Center — Lawrenceville, Georgia, United States
• Dekalb Medical Center-Hillandale — Lithonia, Georgia, United States
• Candler Hospital — Savannah, Georgia, United States
• St. Joseph's Hospital — Savannah, Georgia, United States
• OSF Saint Joseph Medical Center — Bloomington, Illinois, United States
• Bromenn Regional Medical Center — Normal, Illinois, United States
• Bronson Methodist Hospital — Kalamazoo, Michigan, United States
• Saint Luke's Hospital Mid America Brain and Stroke Institute — Kansas City, Missouri, United States
• Research Medical Center — Kansas City, Missouri, United States
• St. Louis University Hospital - Dept of Neurology — St Louis, Missouri, United States
• Nevada Neuroscience Institute at Sunrise — Las Vegas, Nevada, United States
• Enloe Medical Center — Chico, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.