Molecular Associations With Reproductive Failure

Completed

Conditions studied: Spontaneous Abortions, Infertility

In brief

The overall hypothesis to be tested is: women with the molecular phenotype of highly skewed X chromosome inactivation are at increased risk of spontaneous abortion.

Key facts

Study ID

NCT00298116

Run by

University of Pittsburgh

People needed

475

Starts

2000-09-01

Expected to finish

2008-01-01

Last updated by the study team

2014-12-08

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Patients are prospectively ascertained women with either a new pregnancy (specific aim 1), or a spontaneous abortion (specific aim 2).
• Given our enrollment strategy, we anticipate enrolling women between the ages of 18 and 45.

You may not qualify if…

• The study is limited only to females.
• Children are not eligible to participate in this study. Because the patient populations studied are (aim 1) women with primary infertility undergoing fertility treatment and (aim 2) women who have recently had a spontaneous abortion, the research topic is irrelevant to children.

Where it is running

• Magee-Womens Hospital — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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