Behavioral Treatment of Drug Abuse in Severe and Persistent Mental Illness (SPMI) Patients

Completed · Not applicable

Conditions studied: Schizophrenia, Mood Disorders, Substance Dependence

In brief

The main purpose of this study is to determine if the multifaceted treatment for substance abuse in dual disordered patients is more effective in reducing drug use than a supportive control treatment. The researchers will also determine if adding a case management component (Critical Time Intervention; CTI) to the intervention will increase treatment engagement and retention.

Key facts

Study ID

NCT00295139

Run by

University of Maryland, Baltimore

People needed

293

Starts

2005-01-01

Expected to finish

2010-03-01

Last updated by the study team

2022-02-18

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• a diagnosis of schizophrenia or schizoaffective disorder or a diagnosis of other severe mental disorder including bipolar disorder, major depression, or severe anxiety disorder (by definition, the patient has worked 25% or less of the past year; and/or the patient receives payment for mental disability)
• a diagnosis of current dependence for opiates, cocaine, or marijuana
• ability and willingness to attend treatment sessions for 6 months
• ability and willingness to provide consent to participate
• enrolled in mental health care

You may not qualify if…

• documented history of severe neurological disorder or severe head trauma with loss of consciousness
• severe or profound mental retardation as indicated by chart review
• inability to effectively participate in the baseline assessments due to intoxication or psychiatric symptoms on two successive appointments
• had a substantial trial in either intervention of the Evaluation of Behavioral Treatment for Substance Abuse in Schizophrenia protocol (H-20680)
• inability to attend group sessions due to transportation or other logistical problems
• inability to attend scheduled treatment sessions on a regular basis for any reason, or to appropriately participate in research activities due to behavioral or psychiatric problems

Where it is running

• Health Care for the Homeless — Baltimore, Maryland, United States
• University of Maryland, Baltimore — Baltimore, Maryland, United States
• VA Maryland Health Care System — Baltimore, Maryland, United States
• Mosaic Community Services — Catonsville, Maryland, United States

Full record on ClinicalTrials.gov

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