S0429: Docetaxel, Cetuximab, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer
Stopped early · Phase 1
Conditions studied: Lung Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some find tumor cells and kill them or carry tumor-killing substances to them. Others interfere with the ability of tumor cells to grow and spread. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving docetaxel and cetuximab together with radiation therapy may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of docetaxel when given together with cetuximab and radiation therapy in treating patients with stage III non-small cell lung cancer.
Key facts
- Study ID
- NCT00288054
- Run by
- SWOG Cancer Research Network
- People needed
- 24
- Starts
- 2006-04-01
- Expected to finish
- 2012-04-01
- Last updated by the study team
- 2013-01-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- Tibotec Therapeutics - Division of Ortho Biotech Products, LP — Marysville, California, United States
- University of California Davis Cancer Center — Sacramento, California, United States
- University of Colorado Cancer Center at UC Health Sciences Center — Aurora, Colorado, United States
- Veterans Affairs Medical Center - Denver — Denver, Colorado, United States
- Shaw Regional Cancer Center — Edwards, Colorado, United States
- Poudre Valley Hospital — Fort Collins, Colorado, United States
- Valley View Hospital Cancer Center — Glenwood Springs, Colorado, United States
- Montrose Memorial Hospital Cancer Center — Montrose, Colorado, United States
- Eugene M. and Christine E. Lynn Cancer Institute at Boca Raton Community Hospital - West — Boca Raton, Florida, United States
- Eugene M. and Christine E. Lynn Cancer Institute at Boca Raton Community Hospital - Main Campus — Boca Raton, Florida, United States
- Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center — Savannah, Georgia, United States
- Pearlman Comprehensive Cancer Center at South Georgia Medical Center — Valdosta, Georgia, United States
- Cardinal Bernardin Cancer Center at Loyola University Medical Center — Maywood, Illinois, United States
- Hematology Oncology Consultants - Naperville — Naperville, Illinois, United States
- Hospital District Sixth of Harper County — Anthony, Kansas, United States
- Cancer Center of Kansas, PA - Chanute — Chanute, Kansas, United States
- Cancer Center of Kansas, PA - Dodge City — Dodge City, Kansas, United States
- Cancer Center of Kansas, PA - El Dorado — El Dorado, Kansas, United States
- Cancer Center of Kansas - Fort Scott — Fort Scott, Kansas, United States
- Cancer Center of Kansas-Independence — Independence, Kansas, United States
- Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center — Kansas City, Kansas, United States
- Cancer Center of Kansas, PA - Kingman — Kingman, Kansas, United States
- Lawrence Memorial Hospital — Lawrence, Kansas, United States
- Alaska Regional Hospital Cancer Center — Anchorage, Alaska, United States
Full record on ClinicalTrials.gov
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