Novel Glaucoma Diagnostics

Recruiting now

Conditions studied: Glaucoma, Macular Disease

In brief

The purpose of this research is to evaluate novel technologies for the assessment of ocular structure and function, including the scanning device called Optical Coherence Tomography (OCT). We will test the OCT and other devices in their ability to image diseases of the eye and also compare the measurements made with OCT to those of other imaging and visual field devices approved by the Food and Drug Administration (FDA). OCT may be useful for the early diagnosis and monitoring of a variety of types of eye diseases

Key facts

Study ID: NCT00286637
Run by: Wills Eye
People needed: 5000
Starts: 2000-08-01
Expected to finish: 2029-07-31
Last updated by the study team: 2024-08-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Ability to provide informed consent and to understand the study procedures
Healthy volunteers
Age related macular degeneration (AMD), diabetic retinopathy, central serous chorioretinopathy, and/or glaucoma or glaucoma suspects
(AD Sub-Study ONLY): Subjects diagnosed with AD or MCI.

You may not qualify if…

Any medical treatment (e.g., chronic corticosteroid, hydroxychloroquine, chloroquine, thioridazine, canthaxanthine) or conditions that affect VF (e.g., stroke) and retinal thickness other than glaucoma.
Strabismus, nystagmus, or any condition that prevents fixation.
Presence of any media opacities that hinders clinical view of the fundus, and any intraocular non-glaucomatous abnormality
History of ocular trauma or intraocular surgery other than uncomplicated glaucoma interventions or cataract extraction at least 3 months previous to participating in the study.

Where it is running

Wills Eye Hospital — Philadelphia, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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